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Nick Bosa Missed 49ers Game Due to Calf Injury

The defensive star has now missed two consecutive matchups for San Francisco.

Updated on Oct. 4, 2026 in Football

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San Francisco 49ers defensive star Nick Bosa was sidelined for the team’s game against the Denver Broncos due to a lingering calf injury. AI Illustration. Upload story photo >

San Francisco 49ers defensive star Nick Bosa remained sidelined during the team’s game against the Denver Broncos. His absence marks the second straight game he has missed due to an ongoing calf injury.

Why it matters

Bosa’s health remains a central concern for the 49ers defense following his recovery from a torn ACL sustained in 2025. While he is expected to return to the field soon, the team continues to adjust its defensive lineup in his absence.

Nick Bosa has missed two consecutive games due to his calf injury, though he is not expected to remain out for an extended period. The full scope of his return to the lineup remains officially undetermined.

The players

Nick Bosa

The San Francisco 49ers defensive star is currently sidelined with a calf injury.

Ella Ailiff

The partner of Nick Bosa who has shared images of herself wearing team attire.

The details

The 49ers played the Denver Broncos without the defensive standout as he continues to recover from his calf injury. Reports indicate that he is not expected to be out for much longer, despite missing this most recent contest. Public attention has also turned toward his personal life after he and his partner, Ella Ailiff, shared social media updates featuring 49ers team gear.

Timeline

  1. 2025: Nick Bosa suffered a torn ACL and began his relationship with Ella Ailiff.

  2. Week 2 2026: Ella Ailiff watched Bosa play against the Dolphins.

  3. October 4, 2026: The current status of the injury was reported.

Across the Bay

This latest absence follows a pattern of injury management for Bosa that dates back to his 2025 season ACL recovery. The team is currently navigating the impact of these recurring health challenges on their defensive depth.

Fans tracking the 49ers roster will continue to monitor injury reports leading up to the next kickoff. Watch for updates on team status if you are planning to attend upcoming games.

The takeaway

While Bosa remains sidelined, fans should keep an eye on team updates regarding his practice participation to gauge his return. Monitor the team's official injury reports before the next scheduled game to verify his status.

Further reading

Follow the latest team developments and injury updates in our San Francisco Football section.

Source note: This article includes information reported by New York Post.